Clinical Research

Research on PEMF

PEMF at its most focused is a clinically well-evidenced support modality that operates at the level of cellular processes.

As with many clinical and scientific applications, its precise mechanisms are only partially understood.

However there is a compellingly large (and rapidly expanding!) body of high-quality formal research that makes PEMF therapy's application an ever more authoritative proposition.

This research production culminated in the seminal 2021 meta-analysis of Mansourian and Shanei which drew together clinical research findings from over 2400 separate peer-reviewed studies/trials here.

This formal analysis/summation of 20 years of global clinical research provides us with a foundational basis for determining the most clinically effective intensity/frequency levels for PEMF systems.

Intensity Range: 10-100 gauss (1-10 MilliTesla)

Frequency Range: 1-100 Hz

All our devices deliver programmable intensities and frequencies across this range and slightly beyond.

It is worth observing that intensity reduces with distance from the PEMF source. Hence it is necessary therefore that devices are able to produce more than 100 gauss in order to achieve effective assistance deep into the body. Hence our devices are capable of delivering up to 400 gauss.

Source: Mansourian and Shanei here.

This growing research production is providing ever greater clarity as to the biological mechanisms and pathways through which PEMF acts. There are now solid and clinically identifiable cellular markers/processes with clearly measurable outcomes.

And significantly, this is all achieved through the application of a simple, affordable, rapid, safe, non-invasive, drug-free, side-effect free methodology.

The evidence base listed in our Research Library below ranges across studies from osteoporosis to osteoarthritis, and from tendonitis and ligament lesions through to cartilage repair and accelerated bone regeneration, as well as cardiovascular conditions including Coronary Arterial Disease and Hypertension.

Similarly, its growing use among people with a range of non-specific or poorly understood conditions involving pain and inflammatory responses such as Fibromyalgia, CFS and Lupus has now been investigated in detail through numerous double-blind university and hospital led research studies.

PEMF is also increasingly used professionally in the treatment of more acute injuries and disorders such as wound and soft tissue healing, musculoskeletal problems, range of motion limitations and non-union fractures.

Our devices meet the EU Class 2A testing and certification requirements which are obligatory for all medical grade devices (covering quality, safety and efficacy).

And finally we are proud that we were also the first PEMF provider globally to have successfully gone through the new post-Brexit UK Medical Device (Class 2A) registration process.

Andy Morgan
CEO

Research Evidence by Condition

Musculoskeletal disorders -General

(one of my favourite clinical review articles as it sets PEMF’s evolution in detailed historical context before going on to highlight current and future research objectives and potentialities)

https://www.sciencedirect.com/science/article/pii/S0753332220309604

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018879/

https://www.sciencedirect.com/science/article/pii/S0753332220309604

https://pmc.ncbi.nlm.nih.gov/articles/PMC6947624/

Insomnia, sleeplessness, relaxation

Liao J, Wang S, Zhou B, et al. Efficacy and Safety of Pulse Magnetic Therapy System in Insomnia Disorder: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. Psychiatry Investig. Published online June 25, 2023:559-566. doi:10.30773/pi.2022.0362

R, Jaenicke C, Gruenwald J. Impulse magnetic-field therapy for insomnia: a double-blind, placebo-controlled study. Adv Ther. 2001;18(4):174-180.

https://pubmed.ncbi.nlm.nih.gov/11697020/

Chen SH, Chin WC, Huang YS, et al. The effect of electromagnetic field on sleep of patients with nocturia. Medicine. Published online August 12, 2022:e29129. doi:10.1097/md.0000000000029129

Urnukhsaikhan E, Cho H, Mishig-Ochir T, Seo YK, Park JK. Pulsed electromagnetic fields promote survival and neuronal differentiation of human BM-MSCs. Life Sciences. Published online April 2016:130-138. doi:10.1016/j.lfs.2016.02.066

Jiang C, Zhang T, Yue F, Yi M, Gao D. Efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with chronic primary insomnia. Cell Biochem Biophys. 2013;67(1):169-173. doi:10.1007/s12013-013-9529-4

Lai J, Han M, Xu Y, Hu S. Effective treatment of narcolepsy-like symptoms with high-frequency repetitive transcranial magnetic stimulation: A case report. Medicine (Baltimore). 2017;96(46):e8645. doi:10.1097/MD.0000000000008645

Cancer

There is a growing body of evidence finding that PEMF can be helpful for people with certain specific types of cancer. We are not qualified to evaluate to advise of course and strongly advise that you should discuss this with your oncologist before making any decisions. The referenced research papers below should be seen as a start point for such investigation, by a qualified specialist, as to the possible suitability of PEMF for particular, individual cases:

https://pubmed.ncbi.nlm.nih.gov/34311647/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119968/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939155/

https://onlinelibrary.wiley.com/doi/full/10.1002/VIW.20220029

Further Research

Rather than list every study individually, we also recommend referring to the extremely comprehensive searchable research databases available online.

The US National Library of Medicine hosts over 43 pages of searchable PEMF research studies and clinical trials. Simply enter your specific condition together with the word “PEMF”.

Example search: PEMF Fibromyalgia https://www.ncbi.nlm.nih.gov/pmc/?term=pemf

For example this search leads to studies such as: PMC9524818

Suggested reading and textbooks: ScienceDirect PEMF Topic

A more accessible curated list of PEMF research studies can also be found here: Dr Pawluk PEMF Studies

PEMF Therapy Safety

PEMF has been used for many decades and a large number of clinical studies have concluded it to be safe, even at significantly higher intensities than those used by our systems.

For more information and references to clinical safety studies please see:

PEMF Safety Studies